Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 6/20 | 0.74 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.74 |
| ▸ | IL1B | P01584 | 7/20 | 0.46 |
| ▸ | TNF | P01375 | 2/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TRPV3 | Q8NET8 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30181078 | 1.00 | NLRP3 (0.74) | NLRP3KCNH2IL1BTNFCHEK1 | |
| SCHEMBL26435098 | 1.00 | NLRP3 (0.74) | NLRP3KCNH2IL1BTNFCHEK1 | |
| SCHEMBL30624986 | 1.00 | NLRP3 (0.74) | NLRP3KCNH2IL1BTNFCHEK1 | |
| SCHEMBL30181196 | 1.00 | NLRP3 (0.74) | NLRP3KCNH2IL1BTNFCHEK1 | |
| SCHEMBL24855438 | 1.00 | NLRP3 (0.74) | NLRP3KCNH2IL1BTNFCHEK1 | |
| SCHEMBL30356551 | 1.00 | NLRP3 (0.74) | NLRP3KCNH2IL1BTNFCHEK1 | |
| SCHEMBL24855753 | 1.00 | NLRP3 (0.74) | NLRP3KCNH2IL1BTNFCHEK1 | |
| SCHEMBL24855752 | 1.00 | NLRP3 (0.74) | NLRP3KCNH2IL1BTNFCHEK1 | |
| SCHEMBL30180967 | 1.00 | NLRP3 (0.74) | NLRP3KCNH2IL1BTNFCHEK1 | |
| SCHEMBL24855754 | 0.99 | NLRP3 (0.73) | NLRP3KCNH2IL1BTNFCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |
| WO-2023275366-A1 | NLRP3 INFLAMMASOME INHIBITORS | ASTRAZENECA AB (SE) | 2023-01-05 | — | — | WO | disclosed |