SCHEMBL24857047

SCHEMBL24857047

CCC(=O)OOC(C)(C)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.55
ALDH1A1 P00352 2/20 0.47
ALOX15 P16050 1/20 0.47
CYP2C19 P33261 1/20 0.43
HIF1A Q16665 1/20 0.43
OPRM1 P35372 3/20 0.42
DRD2 P14416 1/20 0.42
DRD3 P35462 1/20 0.42
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
MAPT P10636 2/20 0.40
ELANE P08246 1/20 0.40
KMT2A Q03164 1/20 0.40
POLB P06746 2/20 0.39
KCNN4 O15554 1/20 0.39
KCNH2 Q12809 2/20 0.39
CHRM3 P20309 2/20 0.39
OPRD1 P41143 2/20 0.39
MRGPRX2 Q96LB1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29420207 0.84 MAPK1 (0.53) MAPK1ALDH1A1ALOX15CYP2C19HIF1A
SCHEMBL29640504 0.83 MAPK1 (0.48) MAPK1ALDH1A1ALOX15CYP2C19HIF1A
SCHEMBL27338261 0.83 OPRM1 (0.41) MAPK1ALDH1A1ALOX15CYP2C19HIF1A
SCHEMBL42692 0.81 CYP2C19 (0.50) MAPK1ALDH1A1ALOX15CYP2C19HIF1A
SCHEMBL17239837 0.81 MAPK1 (0.50) MAPK1ALDH1A1ALOX15CYP2C19HIF1A
SCHEMBL28543060 0.81 MAPK1 (0.46) MAPK1TSHRKMT2AKDM4E
SCHEMBL30138490 0.81 MAPK1 (0.46) MAPK1TSHRKMT2AKDM4E
SCHEMBL28707657 0.81 MAPK1 (0.46) MAPK1TSHRKMT2AKDM4E
SCHEMBL11586480 0.79 MAPK1 (0.61) MAPK1ALDH1A1ALOX15CYP2C19HIF1A
SCHEMBL28678971 0.79 MAPK1 (0.52) MAPK1ALDH1A1ALOX15CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240218154-A1 OLEFIN-BASED POLYMER AND PEROXIDE COMPOSITIONS WITH EXCELLENT CURE RESPONSE DOW GLOBAL TECHNOLOGIES LLC (US) 2024-07-04 US disclosed
US-20240218154-A1 OLEFIN-BASED POLYMER AND PEROXIDE COMPOSITIONS WITH EXCELLENT CURE RESPONSE DOW GLOBAL TECHNOLOGIES LLC (US) 2024-07-04 US disclosed
CN-116323174-A Multilayer sheet comprising a foamed layer suitable for food packaging 北欧化工公司 2023-06-23 CN disclosed
WO-2023272545-A1 OLEFIN-BASED POLYMER AND PEROXIDE COMPOSITIONS WITH EXCELLENT CURE RESPONSE DOW GLOBAL TECHNOLOGIES LLC (US) 2023-01-05 WO disclosed