Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GUCY1B2 | O75343 | 5/20 | 0.41 |
| ▸ | GUCY1A2 | P33402 | 5/20 | 0.41 |
| ▸ | GUCY1A1 | Q02108 | 5/20 | 0.41 |
| ▸ | GUCY1B1 | Q02153 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3551654 | 0.83 | ALDH1A1 (0.67) | KMT2AALDH1A1SMN1; SMN2CYP1A2MAPT | |
| SCHEMBL6351874 | 0.80 | KMT2A (0.56) | KMT2AALDH1A1SMN1; SMN2CYP1A2GUCY1B2 | |
| SCHEMBL7989395 | 0.80 | KMT2A (0.56) | KMT2AALDH1A1SMN1; SMN2CYP1A2GUCY1B2 | |
| SCHEMBL7978626 | 0.78 | KMT2A (0.54) | KMT2AALDH1A1SMN1; SMN2GUCY1B2GUCY1A2 | |
| SCHEMBL17018449 | 0.74 | SMN1; SMN2 (0.56) | KMT2AALDH1A1SMN1; SMN2CYP1A2GUCY1B2 | |
| SCHEMBL24858415 | 0.74 | KMT2A (0.39) | KMT2AALDH1A1SMN1; SMN2CYP1A2MAPT | |
| SCHEMBL9080957 | 0.72 | KMT2A (0.46) | KMT2AALDH1A1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL24857765 | 0.72 | KDM4E (0.60) | KMT2AALDH1A1SMN1; SMN2CYP1A2GUCY1B2 | |
| SCHEMBL196599 | 0.71 | KMT2A (1.00) | KMT2AALDH1A1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL8315301 | 0.71 | KMT2A (1.00) | KMT2AALDH1A1SMN1; SMN2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002414-A1 | AZAHETEROARYL COMPOUND AND APPLICATION THEREOF | SHANGHAI BLUERAY BIOPHARMA CO., LTD. (CN) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002414-A1 | AZAHETEROARYL COMPOUND AND APPLICATION THEREOF | EZH2, EED, SUZ12 | KMT2A 85/4885ALDH1A1 1813/4885SMN1; SMN2 1471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.