Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL416480 | 0.92 | BCHE (0.48) | BCHEACHETACR1RAB9ARIPK1 | |
| SCHEMBL416332 | 0.91 | BCHE (0.49) | BCHEACHEEGFRERBB2NPC1 | |
| SCHEMBL412947 | 0.89 | FOLH1 (0.47) | NPC1RAB9AFOLH1RIPK1MTOR | |
| SCHEMBL2486080 | 0.86 | NPC1 (0.37) | BCHEACHENPC1RAB9AALDH1A1 | |
| SCHEMBL417118 | 0.83 | BCHE (0.39) | BCHEACHEEGFRERBB2TACR1 | |
| SCHEMBL418204 | 0.82 | BCHE (0.40) | BCHEACHEEGFRERBB2RAB9A | |
| SCHEMBL415110 | 0.82 | TDP1 (0.48) | NPC1RAB9ARIPK1ALDH1A1LTB4R2 | |
| SCHEMBL416307 | 0.82 | RAB9A (0.41) | BCHEACHENPC1RAB9AFOLH1 | |
| SCHEMBL413456 | 0.82 | RAB9A (0.52) | NPC1RAB9AMTORALDH1A1LMNA | |
| SCHEMBL418467 | 0.82 | NPC1 (0.59) | BCHEACHENPC1RAB9ARIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376431-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | LABORATOIRE BIODIM (FR) | 2011-10-19 | — | — | EP | claimed |
| WO-2010066847-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | CELLVIR (FR) | 2010-06-17 | — | — | WO | claimed |