Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.40 |
| ▸ | MGAM | O43451 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 4/20 | 0.40 |
| ▸ | AGL | P35573 | 3/20 | 0.40 |
| ▸ | SI | P14410 | 3/20 | 0.40 |
| ▸ | PYGL | P06737 | 2/20 | 0.40 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.40 |
| ▸ | FUCA1 | P04066 | 4/20 | 0.39 |
| ▸ | GBA2 | Q9HCG7 | 3/20 | 0.39 |
| ▸ | GBA1 | P04062 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LCT | P09848 | 2/20 | 0.39 |
| ▸ | GBA3 | Q9H227 | 2/20 | 0.39 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.39 |
| ▸ | MAN2B2 | Q9Y2E5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TREH | O43280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30680861 | 1.00 | GAA (0.40) | GAAMGAMGLAAGLSI | |
| SCHEMBL24858551 | 1.00 | GAA (0.40) | GAAMGAMGLAAGLSI | |
| SCHEMBL27044745 | 1.00 | GAA (0.40) | GAAMGAMGLAAGLSI | |
| SCHEMBL30803905 | 0.83 | GLB1 (0.40) | AGLGLB1 | |
| SCHEMBL30803876 | 0.83 | GLB1 (0.40) | AGLGLB1 | |
| SCHEMBL25165592 | 0.74 | — | — | |
| SCHEMBL19781210 | 0.65 | — | — | |
| SCHEMBL25646625 | 0.65 | — | — | |
| SCHEMBL29936905 | 0.65 | MGAM (0.34) | GAAMGAMSIFUCA1GBA1 | |
| SCHEMBL29883136 | 0.64 | PKM (0.41) | MEN1ALOX15KMT2AALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023030385-A1 | PYRIMIDINE-FUSED CYCLIC COMPOUND AND PREPARATION METHOD AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-03-09 | — | — | WO | disclosed |
| WO-2023274383-A1 | KRAS G12D INHIBITOR AND USE THEREOF | 上海迪诺医药科技有限公司 | 2023-01-05 | — | — | WO | disclosed |