Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.40 |
| ▸ | SKP1 | P63208 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24858709 | 0.85 | CA12 (0.47) | GABRA5CA12CA1CA2CA9 | |
| SCHEMBL24858710 | 0.83 | MAPT (0.54) | GABRA5CA12CA1CA2CA9 | |
| SCHEMBL30131245 | 0.78 | CA12 (0.50) | GABRA5CA12CA1CA2CA9 | |
| SCHEMBL18530385 | 0.78 | CA12 (0.50) | GABRA5CA12CA1CA2CA9 | |
| SCHEMBL1092214 | 0.78 | MAPT (0.48) | GABRA5EPHX2 | |
| SCHEMBL18530389 | 0.77 | CA12 (0.49) | GABRA5CA12CA1CA2CA9 | |
| SCHEMBL18289997 | 0.77 | CA12 (0.49) | GABRA5CA12CA1CA2CA9 | |
| SCHEMBL30564446 | 0.77 | CA12 (0.49) | GABRA5CA12CA1CA2CA9 | |
| SCHEMBL2715852 | 0.77 | EPHX2 (0.54) | SCN9AEPHX2KCNH2SCN5A | |
| SCHEMBL528927 | 0.77 | CA12 (0.52) | GABRA5CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023272410-A1 | ERα RECEPTOR COVALENT BINDING ANTAGONIST | 北京盛诺基医药科技股份有限公司 | 2023-01-05 | — | — | WO | disclosed |