Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 5/20 | 0.48 |
| ▸ | CA1 | P00915 | 5/20 | 0.48 |
| ▸ | CA2 | P00918 | 5/20 | 0.48 |
| ▸ | CA9 | Q16790 | 5/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP1 | P63208 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31286719 | 0.91 | CA12 (0.51) | MAPTGABRA5L3MBTL1CA12CA1 | |
| SCHEMBL24858709 | 0.89 | CA12 (0.47) | GABRA5L3MBTL1CA12CA1CA2 | |
| SCHEMBL30131245 | 0.84 | CA12 (0.50) | MAPTGABRA5L3MBTL1CA12CA1 | |
| SCHEMBL18530385 | 0.84 | CA12 (0.50) | GABRA5L3MBTL1CA12CA1CA2 | |
| SCHEMBL24858712 | 0.83 | GABRA5 (0.46) | GABRA5CA12CA1CA2CA9 | |
| SCHEMBL18530389 | 0.83 | CA12 (0.49) | GABRA5CA12CA1CA2CA9 | |
| SCHEMBL30564446 | 0.83 | CA12 (0.49) | GABRA5CA12CA1CA2CA9 | |
| SCHEMBL18289997 | 0.83 | CA12 (0.49) | GABRA5L3MBTL1CA12CA1CA2 | |
| SCHEMBL528927 | 0.83 | CA12 (0.52) | GABRA5CA12CA1CA2CA9 | |
| SCHEMBL29606964 | 0.82 | CA12 (0.48) | GABRA5L3MBTL1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023272410-A1 | ERα RECEPTOR COVALENT BINDING ANTAGONIST | 北京盛诺基医药科技股份有限公司 | 2023-01-05 | — | — | WO | disclosed |