SCHEMBL24858894

SCHEMBL24858894

CCCCCCOP(=O)(S)OC1C[C@H](n2cc(C)c(=O)[nH]c2=O)O[C@@H]1COP(=O)(S)OC1C[C@H](n2cc(C)c(=O)[nH]c2=O)O[C@@H]1COP(=O)(S)OC1C[C@H](n2cnc3c(N)ncnc32)O[C@@H]1COP(=O)(S)OC1C[C@H](n2cc(C)c(N)nc2=O)O[C@@H]1COP(=O)(S)OC1C[C@H](n2cnc3c(N)ncnc32)O[C@@H]1COP(=O)(S)OC1C[C@H](n2cnc3c(=O)[nH]c(N)nc32)O[C@@H]1CC

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 2/20 0.52
▸ DTYMK P23919 4/20 0.48
▸ F2 P00734 4/20 0.48
▸ POLB P06746 1/20 0.41
▸ P2RY2 P41231 1/20 0.39
▸ P2RY4 P51582 1/20 0.39
▸ P2RY6 Q15077 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27103942 0.93 TERT (0.53) TERTDTYMKF2POLBP2RY2
SCHEMBL27062376 0.93 TERT (0.53) TERTDTYMKF2POLBP2RY2
SCHEMBL26401760 0.93 TERT (0.53) TERTDTYMKF2POLBP2RY2
SCHEMBL25456890 0.93 TERT (0.53) TERTDTYMKF2POLBP2RY2
SCHEMBL16692051 0.93 TERT (0.53) TERTDTYMKF2POLBP2RY2
SCHEMBL26401791 0.93 TERT (0.53) TERTDTYMKF2POLBP2RY2
SCHEMBL18993187 0.93 TERT (0.53) TERTDTYMKF2POLBP2RY2
SCHEMBL27103969 0.93 TERT (0.53) TERTDTYMKF2POLBP2RY2
SCHEMBL17231693 0.93 TERT (0.53) TERTDTYMKF2POLBP2RY2
SCHEMBL27104050 0.93 TERT (0.53) TERTDTYMKF2POLBP2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11547718-B2 Modulators of FOXP3 expression IONIS PHARMACEUTICALS, INC. (US) 2023-01-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11547718-B2 Modulators of FOXP3 expression BCOR, CD4, IKZF1 TERT 1132/4885DTYMK 1104/4885F2 4765/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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