Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15200926 | 0.86 | MEN1 (0.41) | ALDH1A1KDM4ETDP1MEN1KMT2A | |
| SCHEMBL9557849 | 0.85 | KDM4E (0.48) | ALDH1A1KDM4ETDP1MEN1KMT2A | |
| SCHEMBL5788461 | 0.84 | MEN1 (0.40) | ALDH1A1MEN1KMT2ATSHRGLA | |
| SCHEMBL11290508 | 0.80 | KDM4E (0.41) | ALDH1A1KDM4ETDP1MEN1KMT2A | |
| SCHEMBL16099384 | 0.79 | KDM4E (0.68) | ALDH1A1KDM4ETDP1MEN1KMT2A | |
| SCHEMBL11983169 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KDM4EMEN1KMT2ATSHR | |
| SCHEMBL2485564 | 0.75 | MEN1 (0.45) | ALDH1A1KDM4EMEN1KMT2ATSHR | |
| SCHEMBL11288880 | 0.74 | ALDH1A1 (0.60) | ALDH1A1KDM4EMEN1KMT2ATSHR | |
| SCHEMBL11292140 | 0.74 | KDM4E (0.38) | ALDH1A1KDM4ETDP1MEN1KMT2A | |
| SCHEMBL11286613 | 0.74 | KDM4E (0.66) | ALDH1A1KDM4ETDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376456-A2 | HIGHLY PURE LAQUINIMOD OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Actavis Group Ptc Ehf (IS) | 2011-10-19 | — | — | EP | claimed |
| WO-2010070449-A2 | HIGHLY PURE LAQUINIMOD OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ACTAVIS GROUP PTC EHF (IS) | 2010-06-24 | — | — | WO | claimed |
| EP-2376456-A2 | HIGHLY PURE LAQUINIMOD OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Actavis Group Ptc Ehf (IS) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010070449-A2 | HIGHLY PURE LAQUINIMOD OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ACTAVIS GROUP PTC EHF (IS) | 2010-06-24 | — | — | WO | disclosed |