Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CASP2 | P42575 | 1/20 | 0.33 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25479251 | 0.77 | MAPK1 (0.37) | KDM4AKDM4CEPHX1ADRA1AKDM4E | |
| SCHEMBL26224162 | 0.77 | MAPK1 (0.37) | KDM4AKDM4CEPHX1ADRA1AKDM4E | |
| SCHEMBL22794331 | 0.77 | MAPK1 (0.37) | KDM4AKDM4CEPHX1ADRA1AKDM4E | |
| SCHEMBL17942985 | 0.76 | KDM4A (0.63) | KDM4AKDM4CADRA1APRMT1ALDH1A1 | |
| SCHEMBL22954504 | 0.76 | PAOX (0.57) | KDM4AKDM4CEPHX1ADRA1AKDM4E | |
| SCHEMBL11303506 | 0.76 | PAOX (0.57) | KDM4AKDM4CEPHX1ADRA1AKDM4E | |
| SCHEMBL24812346 | 0.76 | PAOX (0.57) | KDM4AKDM4CEPHX1ADRA1AKDM4E | |
| SCHEMBL23279213 | 0.76 | KDM4A (0.48) | KDM4AKDM4CEPHX1ADRA1AKDM4E | |
| SCHEMBL24804427 | 0.76 | KDM4A (0.48) | KDM4AKDM4CEPHX1ADRA1AKDM4E | |
| SCHEMBL18932735 | 0.76 | PAOX (0.57) | KDM4AKDM4CEPHX1ADRA1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3408271-B1 | MAYTANSINOID DERIVATIVES, CONJUGATES THEREOF, AND METHODS OF USE | REGENERON PHARMA (US) | 2023-01-11 | — | — | EP | disclosed |