Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 7/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | PDE9A | O76083 | 5/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | PDE1A | P54750 | 1/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24861081 | 0.89 | CRBN (0.53) | CRBNDDB1 | |
| SCHEMBL24861325 | 0.84 | CRBN (0.43) | CRBNDDB1 | |
| SCHEMBL26250780 | 0.81 | CRBN (0.53) | CRBNDDB1 | |
| SCHEMBL24861335 | 0.78 | CRBN (0.41) | CRBNDDB1ABL1 | |
| SCHEMBL24861071 | 0.77 | CRBN (0.43) | CRBNDDB1 | |
| SCHEMBL24861295 | 0.77 | CRBN (0.46) | CRBNDDB1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL27253772 | 0.75 | CRBN (0.42) | CRBNDDB1 | |
| SCHEMBL27253859 | 0.74 | CRBN (0.35) | CRBNDDB1GSK3B | |
| SCHEMBL26250801 | 0.72 | CYP1A2 (0.38) | CYP1A1CYP1A2CYP1B1PDE5APDE9A | |
| SCHEMBL24861331 | 0.72 | CRBN (0.41) | CRBNDDB1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112120-A1 | DEGRADER INCLUDING NOVEL C-MET PROTEIN LIGAND AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | 주식회사 이노큐어테라퓨틱스 | 2024-05-30 | — | — | WO | disclosed |
| EP-4116298-A1 | PIPERIDINEDIONE DERIVATIVE | Innocure Therapeutics, Inc. (KR) | 2023-01-11 | — | — | EP | disclosed |