SCHEMBL24861081

SCHEMBL24861081

COc1ccc2c(=O)n(C3CCC(=O)NC3=O)ncc2c1

nearest known ligand 0.53

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 19/20 0.53
▸ DDB1 Q16531 17/20 0.53
▸ IKZF2 Q9UKS7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26250780 0.91 CRBN (0.53) CRBNDDB1IKZF2
SCHEMBL24861079 0.89 CRBN (0.41) CRBNDDB1
SCHEMBL26248314 0.83 CRBN (0.56) CRBNDDB1
SCHEMBL26247581 0.83 CRBN (0.56) CRBNDDB1
SCHEMBL26248254 0.83 CRBN (0.56) CRBNDDB1
SCHEMBL24861377 0.83 CRBN (0.56) CRBNDDB1
SCHEMBL31538742 0.80 CRBN (0.53) CRBNDDB1
SCHEMBL26250141 0.80 CRBN (0.72) CRBNDDB1
Hydrochloric Acid SCHEMBL31330885 0.80 SLC6A2 (0.46) CRBNDDB1
SCHEMBL31091770 0.80 CRBN (0.45) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12384756-B2 Piperidinedione derivatives INNOCURE THERAPEUTICS, INC. (KR) 2025-08-12 — — US claimed
EP-4640686-A1 DEGRADER FOR DEGRADING BRD PROTEIN AND PHARMACEUTICAL COMPOSITION CONTAINING SAME Innocure Therapeutics, Inc. (KR) 2025-10-29 — — EP disclosed
EP-4624472-A1 DEGRADER INCLUDING NOVEL C-MET PROTEIN LIGAND AND PHARMACEUTICAL COMPOSITION INCLUDING SAME Innocure Therapeutics, Inc. (KR) 2025-10-01 — — EP disclosed
EP-4624466-A1 DEGRADER FOR DECOMPOSING CMET PROTEIN, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Innocure Therapeutics, Inc. (KR) 2025-10-01 — — EP disclosed
WO-2024112120-A1 DEGRADER INCLUDING NOVEL C-MET PROTEIN LIGAND AND PHARMACEUTICAL COMPOSITION INCLUDING SAME 주식회사 이노큐어테라퓨틱스 2024-05-30 — — WO disclosed
US-20230295105-A1 PIPERIDINEDIONE DERIVATIVES INNOCURE THERAPEUTICS, INC. (KR) 2023-09-21 — — US disclosed
CN-116323619-A Piperidinedione derivatives 因诺库尔治疗公司 2023-06-23 — — CN disclosed
EP-4116298-A1 PIPERIDINEDIONE DERIVATIVE Innocure Therapeutics, Inc. (KR) 2023-01-11 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230295105-A1 PIPERIDINEDIONE DERIVATIVES CRBN, CUL1, PSMB10 CRBN 1/4885DDB1 868/4885IKZF2 86/4885
US-12384756-B2 Piperidinedione derivatives CRBN, CUL1, PSMB10 CRBN 1/4885DDB1 868/4885IKZF2 86/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback