SCHEMBL2486211

SCHEMBL2486211

CC(O)OC(=O)/C=C\C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 10/20 0.71
TSHR P16473 3/20 0.43
TP53 P04637 2/20 0.43
EGLN1 Q9GZT9 1/20 0.43
EGLN3 Q9H6Z9 1/20 0.43
ALDH1A1 P00352 4/20 0.41
GAA P10253 1/20 0.41
TDP1 Q9NUW8 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MAPT P10636 1/20 0.41
GABRP O00591 2/20 0.39
GABRD O14764 2/20 0.39
GABRA1 P14867 2/20 0.39
GABRB1 P18505 2/20 0.39
GABRG2 P18507 2/20 0.39
GABRB3 P28472 2/20 0.39
GABRA5 P31644 2/20 0.39
GABRA3 P34903 2/20 0.39
GABRA2 P47869 2/20 0.39
GABRB2 P47870 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2486215 1.00 HCAR2 (0.71) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL27341759 1.00 HCAR2 (0.71) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL5053871 0.90 HCAR2 (0.54) HCAR2TSHRTP53KEAP1NFE2L2
SCHEMBL2911353 0.90 HCAR2 (0.54) HCAR2TSHRTP53KEAP1NFE2L2
SCHEMBL6835137 0.90 HCAR2 (0.54) HCAR2TSHRTP53KEAP1NFE2L2
Maleic Acid SCHEMBL28193787 0.85 HCAR2 (0.52) HCAR2TSHRTP53EGLN1EGLN3
Fumaric Acid SCHEMBL956151 0.85 HCAR2 (0.52) HCAR2TSHRTP53EGLN1EGLN3
Isopropyl Fumarate SCHEMBL313612 0.83 HCAR2 (1.00) HCAR2TSHRTP53EGLN1EGLN3
Isopropyl Fumarate SCHEMBL690596 0.83 HCAR2 (1.00) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL12059695 0.83 HCAR2 (0.74) HCAR2TSHRTP53EGLN1EGLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247659-B2 Photosensitive resin composition CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-07-24 US claimed
EP-4674894-A2 COPOLYMERS OF N-VINYLPYRROLIDONE WITH FUNCTIONALIZED MALEIC ACID MOIETIES Hemoteq AG (DE) 2026-01-07 EP disclosed
EP-4663688-A2 CROSSLINKERS Hemoteq AG (DE) 2025-12-17 EP disclosed
EP-4584243-B1 CROSSLINKERS HEMOTEQ AG (DE) 2025-11-05 EP disclosed
EP-4584243-A1 CROSSLINKERS Hemoteq AG (DE) 2025-07-16 EP disclosed
EP-4584244-A1 COPOLYMERS OF N-VINYLPYRROLIDONE WITH FUNCTIONALIZED MALEIC ACID MOIETIES Hemoteq AG (DE) 2025-07-16 EP disclosed
EP-4584245-A1 COPOLYMERS OF N-VINYLPYRROLIDONE WITH FUNCTIONALIZED MALEIC ACID MOIETIES Hemoteq AG (DE) 2025-07-16 EP disclosed
WO-2025056813-A1 COPOLYMERS OF N-VINYLPYRROLIDONE WITH FUNCTIONALIZED MALEIC ACID MOIETIES HEMOTEQ AG (DE) 2025-03-20 WO disclosed
WO-2025056814-A1 CROSSLINKERS HEMOTEQ AG (DE) 2025-03-20 WO disclosed
WO-2025056815-A1 COPOLYMERS OF N-VINYLPYRROLIDONE WITH FUNCTIONALIZED MALEIC ACID MOIETIES HEMOTEQ AG (DE) 2025-03-20 WO disclosed
US-20040192804-A1 Photosensitive resin composition IGM GROUP B.V. (NL) 2004-09-30 US disclosed
EP-1410109-A1 PHOTOSENSITIVE RESIN COMPOSITION Ciba SC Holding AG (CH) 2004-04-21 EP disclosed
WO-2003010602-A1 PHOTOSENSITIVE RESIN COMPOSITION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-02-06 WO disclosed
EP-0818470-B1 PROCESS FOR PREPARING SOLVENT-TYPE ACRYLIC PRESSURE-SENSITIVE ADHESIVES AND MEDICAL PRESSURE-SENSITIVE ADHESIVE SEIKISUI CHEMICAL CO LTD (JP) 2002-08-07 EP disclosed
US-5886122-A BIOCOMPATIBLE ALKYL (METH)ACRYLATE COPOLYMER; ODORLESS, LESS IRRITATION TO HUMAN BODY; TAPES, LABELS, SHEETS SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1999-03-23 US disclosed
US-5773541-A BLEND CONTAINING SURFACTANT IN AQUEOUS SOLUTION BASF AKTIENGESELLSCHAFT (DE) 1998-06-30 US disclosed
EP-0818470-A1 PROCESS FOR PREPARING SOLVENT-TYPE ACRYLIC PRESSURE-SENSITIVE ADHESIVES AND MEDICAL PRESSURE-SENSITIVE ADHESIVE SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1998-01-14 EP disclosed
US-4572869-A Microcapsular opacifiers and method for their production PPG INDUSTRIES, INC. (US) 1986-02-25 US disclosed
US-4153640-A POLYALKYLHYDROGENSILOXANE, HYDROXYALKYL ACRYLATE CIBA-GEIGY CORPORATION (US) 1979-05-08 US disclosed
US-4007141-A Opaque, non-pigmented microporous film and process and composition for preparing same PPG INDUSTRIES, INC. (US) 1977-02-08 US disclosed