Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3241157 | 0.92 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2SPHK1EPHX1 | |
| SCHEMBL2485850 | 0.92 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2SPHK1EPHX1 | |
| SCHEMBL3241159 | 0.92 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2SPHK1EPHX1 | |
| SCHEMBL3245975 | 0.92 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2SPHK1EPHX1 | |
| SCHEMBL3241128 | 0.92 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2SPHK1EPHX1 | |
| SCHEMBL3231987 | 0.92 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2SPHK1EPHX1 | |
| SCHEMBL3236864 | 0.92 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2SPHK1EPHX1 | |
| SCHEMBL29593 | 0.92 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2SPHK1EPHX1 | |
| SCHEMBL6925925 | 0.90 | ALDH1A1 (0.45) | ALDH1A1TDP1SMN1; SMN2SPHK1EPHX1 | |
| SCHEMBL3238846 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TDP1SMN1; SMN2TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1967217-B1 | Antimicrobial medical product, method for manufacture and application thereof | AESCULAP AG (DE) | 2011-10-26 | — | — | EP | claimed |
| EP-1967217-A2 | Antimicrobial medical product, method for manufacture and application thereof | AESCULAP AG (DE) | 2008-09-10 | — | — | EP | claimed |