Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.53 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.53 |
| ▸ | USP30 | Q70CQ3 | 8/20 | 0.46 |
| ▸ | CTSV | O60911 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16993979 | 0.89 | PABPC1 (0.66) | PABPC1EIF4HUSP30CTSVCTSL | |
| SCHEMBL16999319 | 0.89 | PABPC1 (0.66) | PABPC1EIF4HUSP30CTSVCTSL | |
| SCHEMBL16999362 | 0.79 | KDM4E (0.53) | PABPC1EIF4HUSP30CTSVCTSL | |
| SCHEMBL16994018 | 0.79 | KDM4E (0.53) | PABPC1EIF4HUSP30CTSVCTSL | |
| SCHEMBL16999703 | 0.79 | KDM4E (0.53) | PABPC1EIF4HUSP30CTSVCTSL | |
| SCHEMBL16994059 | 0.79 | KDM4E (0.53) | PABPC1EIF4HUSP30CTSVCTSL | |
| SCHEMBL16994008 | 0.77 | USP30 (0.59) | PABPC1EIF4HUSP30KDM4EALDH1A1 | |
| SCHEMBL16999330 | 0.77 | USP30 (0.59) | PABPC1EIF4HUSP30KDM4EALDH1A1 | |
| SCHEMBL16994022 | 0.74 | TRPV1 (0.53) | — | |
| SCHEMBL16999333 | 0.74 | TRPV1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102193-B1 | ANTIBACTERIAL AGENTS: N(ALPHA)-AROYL-N-ARYL-PHENYLALANINAMIDES | UNIV RUTGERS (US) | 2023-01-11 | — | — | EP | disclosed |