SCHEMBL2486319

SCHEMBL2486319

CC(O)(O)OC(=O)/C=C\C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 11/20 0.52
TSHR P16473 4/20 0.43
TP53 P04637 1/20 0.43
EGLN1 Q9GZT9 1/20 0.43
EGLN3 Q9H6Z9 1/20 0.43
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
GABRP O00591 2/20 0.34
GABRD O14764 2/20 0.34
GABRA1 P14867 2/20 0.34
GABRB1 P18505 2/20 0.34
GABRG2 P18507 2/20 0.34
GABRB3 P28472 2/20 0.34
GABRA5 P31644 2/20 0.34
GABRA3 P34903 2/20 0.34
GABRA2 P47869 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1272868 1.00 HCAR2 (0.52) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL9315123 1.00 HCAR2 (0.52) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL8157810 0.90 HCAR2 (0.43) HCAR2TSHRALDH1A1KEAP1NFE2L2
SCHEMBL9315118 0.90 HCAR2 (0.43) HCAR2TSHRALDH1A1KEAP1NFE2L2
Maleic Acid SCHEMBL17821261 0.85 HCAR2 (0.41) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL1964699 0.83 HCAR2 (0.54) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL642104 0.83 HCAR2 (0.54) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL642105 0.83 HCAR2 (0.54) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL28920930 0.81 HCAR2 (0.52) HCAR2TSHRTP53EGLN1EGLN3
Ethane SCHEMBL29288096 0.81 HCAR2 (0.52) HCAR2TSHRTP53EGLN1EGLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2804887-B1 POLYESTER POLYOLS CONTAINING DIELS-ALDER OR ENE ADDUCTS STEPAN CO (US) 2017-03-01 EP claimed
US-20140378570-A1 Polyester Polyols Containing Diels-Alder or Ene Adducts STEPAN COMPANY 2014-12-25 US claimed
EP-2804887-A1 POLYESTER POLYOLS CONTAINING DIELS-ALDER OR ENE ADDUCTS Stepan Company (US) 2014-11-26 EP claimed
WO-2013109834-A1 POLYESTER POLYOLS CONTAINING DIELS-ALDER OR ENE ADDUCTS STEPAN COMPANY (US) 2013-07-25 WO claimed
EP-0636743-B1 Process for dyeing of wool-containing fibre materials CIBA SC HOLDING AG (CH) 1999-12-29 EP claimed
EP-0425436-B1 Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof CIBA GEIGY AG (CH) 1996-12-27 EP claimed
US-5514727-A OPTICAL FIBER COATINGS, POLYETHER OR POLYESTER POLYOLS ENDCAPPED WITH HYDROXY VINYL ETHER ALLIEDSIGNAL INC. (US) 1996-05-07 US claimed
US-5460630-A Process for dyeing fibrous materials made of or containing wool CIBA-GEIGY CORPORATION (US) 1995-10-24 US claimed
EP-0425436-A2 Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof CIBA-GEIGY AG (CH) 1991-05-02 EP claimed
US-5010141-A Heat- or UV-curable acrylic resins; coatings; films; biocompatible, water-swelling, oxygen-permeable contact lenses CIBA-GEIGY CORPORATION (US) 1991-04-23 US claimed
EP-4674894-A2 COPOLYMERS OF N-VINYLPYRROLIDONE WITH FUNCTIONALIZED MALEIC ACID MOIETIES Hemoteq AG (DE) 2026-01-07 EP disclosed
EP-4663688-A2 CROSSLINKERS Hemoteq AG (DE) 2025-12-17 EP disclosed
EP-4584243-B1 CROSSLINKERS HEMOTEQ AG (DE) 2025-11-05 EP disclosed
EP-4584243-A1 CROSSLINKERS Hemoteq AG (DE) 2025-07-16 EP disclosed
EP-4584245-A1 COPOLYMERS OF N-VINYLPYRROLIDONE WITH FUNCTIONALIZED MALEIC ACID MOIETIES Hemoteq AG (DE) 2025-07-16 EP disclosed
US-4956421-A COPOLYMERIZATION OF UNSATURATED ACIDS WITH ALKYLENE OXIDES IN THE PRESENCE OF A THIOETHER OR MERCAPTAN CATALYST BASF AKTIENGESELLSCHAFT (DE) 1990-09-11 US disclosed
US-4808447-A Preserved flowers and other substrates BAKER MARION A (US) 1989-02-28 US disclosed
EP-0279108-A2 Process for preserving plants or parts thereof Baker, Marion A. (US) 1988-08-24 EP disclosed
US-4605712-A Unsaturated polysiloxanes and polymers thereof CIBA-GEIGY CORPORATION (US) 1986-08-12 US disclosed
US-4486577-A Strong, silicone containing polymers with high oxygen permeability CIBA-GEIGY CORPORATION (US) 1984-12-04 US disclosed