SCHEMBL642105

SCHEMBL642105

CC(C)(C)OC(=O)C=CC(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 10/20 0.54
TSHR P16473 3/20 0.45
TP53 P04637 1/20 0.45
EGLN1 Q9GZT9 1/20 0.45
EGLN3 Q9H6Z9 1/20 0.45
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
KEAP1 Q14145 1/20 0.38
NFE2L2 Q16236 1/20 0.38
GABRP O00591 2/20 0.36
GABRD O14764 2/20 0.36
GABRA1 P14867 2/20 0.36
GABRB1 P18505 2/20 0.36
GABRG2 P18507 2/20 0.36
GABRB3 P28472 2/20 0.36
GABRA5 P31644 2/20 0.36
GABRA3 P34903 2/20 0.36
GABRA2 P47869 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1964699 1.00 HCAR2 (0.54) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL642104 1.00 HCAR2 (0.54) HCAR2TSHRTP53EGLN1EGLN3
Ethane SCHEMBL17667147 0.98 HCAR2 (0.52) HCAR2TSHRTP53EGLN1EGLN3
Methane SCHEMBL9860828 0.98 HCAR2 (0.52) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL28920930 0.98 HCAR2 (0.52) HCAR2TSHRTP53EGLN1EGLN3
Ethane SCHEMBL29288096 0.98 HCAR2 (0.52) HCAR2TSHRTP53EGLN1EGLN3
Propane SCHEMBL7780510 0.93 HCAR2 (0.54) HCAR2TSHRTP53EGLN1EGLN3
Cyclohexane SCHEMBL10616072 0.93 HCAR2 (0.48) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL8405431 0.89 HCAR2 (0.45) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL8405432 0.89 HCAR2 (0.45) HCAR2TSHRTP53EGLN1EGLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 740 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12139679-B2 Lubricity modifier for fuels and application thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2024-11-12 US claimed
US-20230151290-A1 LUBRICITY MODIFIER FOR FUELS AND APPLICATION THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2023-05-18 US claimed
CN-116003690-A Polyolefin greenhouse film and preparation method thereof 中国石油化工股份有限公司 2023-04-25 CN claimed
CN-116003689-A Modified polyolefin polymer and polyolefin film prepared from same 中国石油化工股份有限公司 2023-04-25 CN claimed
EP-4130206-A1 FUEL LUBRICITY IMPROVER AND APPLICATION THEREOF China Petroleum & Chemical Corporation (CN) 2023-02-08 EP claimed
CN-106916503-B Single-component varnish composition, preparation method and application thereof 廊坊立邦涂料有限公司 2020-03-17 CN claimed
CN-106928410-B Organic silicon modified acrylic resin with high solid content and low viscosity, preparation method and application 立邦涂料(中国)有限公司 2020-02-07 CN claimed
CN-109790276-A The method for preparing elastomer 科思创德国股份有限公司 2019-05-21 CN claimed
EP-3208301-B1 RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME TOSOH CORP (JP) 2019-04-03 EP claimed
US-10126478-B2 Resin composition and optical compensation film using same TOSOH CORPORATION (JP) 2018-11-13 US claimed
CN-105199243-A Inflame-retardant mine cabtyre cable sheath material ANHUI LAND GROUP CO LTD 2015-12-30 CN claimed
CN-104673370-A Oxidation-extraction combined desulfurization method based on ionic liquid UNIV BEIJING CHEMICAL 2015-06-03 CN claimed
CN-101821039-B Method for producing separable and redispersible transition metal nanoparticles and use thereof as IR absorbers BASF AG 2013-07-17 CN claimed
US-20110177454-A1 RESIST MATERIAL AND PATTERN FORMATION METHOD USING THE RESIST MATERIAL PANASONIC CORPORATION (JP) 2011-07-21 US claimed
CN-101821039-A Isolatable and redispersible transition metal nanoparticles, their preparation and use as IR absorbers BASF AG 2010-09-01 CN claimed
CN-101061148-A Curable formulations, cured compositions, and articles derived therefrom GEN ELECTRIC (US) 2007-10-24 CN claimed
CN-1160382-C Process for producing polypropylene resin with controlled rheology ���з��ɹ�˾ 2004-08-04 CN claimed
CN-1357011-A Method for prodn. of controlled rheological polypropylene resin ATOFINA (FR) 2002-07-03 CN claimed
US-6306990-B1 MALEIC ACID DIESTER MONOMERS FOR POLYMER FILMS AND HEAT STABLE POLYMERS SIEMENS AKTIENGESELLSCHAFT (DE) 2001-10-23 US claimed
US-4284707-A Photocurable light-sensitive composition SOMAR MANUFACTURING CO., LTD. (JP) 1981-08-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12139679-B2 Lubricity modifier for fuels and application thereof F12, ACADM, ADH1A HCAR2 341/4885TSHR 3500/4885TP53 1546/4885
US-20230151290-A1 LUBRICITY MODIFIER FOR FUELS AND APPLICATION THEREOF F12, ACADM, ADH1A HCAR2 341/4885TSHR 3500/4885TP53 1546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.