Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.56 |
| ▸ | F12 | P00748 | 1/20 | 0.56 |
| ▸ | NCF1 | P14598 | 1/20 | 0.56 |
| ▸ | NOS3 | P29474 | 1/20 | 0.56 |
| ▸ | NOS1 | P29475 | 1/20 | 0.56 |
| ▸ | NOS2 | P35228 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30100779 | 1.00 | PLAU (0.56) | PLAUCYP2A6F12NCF1NOS3 | |
| Ammonia Solution, Strong SCHEMBL28213835 | 0.98 | PLAU (0.54) | PLAUCYP2A6F12NCF1NOS3 | |
| Iodide SCHEMBL26934065 | 0.98 | PLAU (0.54) | PLAUCYP2A6F12NCF1NOS3 | |
| SCHEMBL27445665 | 0.94 | CYP2A6 (0.55) | PLAUCYP2A6F12NCF1NOS3 | |
| Bicarbonate SCHEMBL28387859 | 0.88 | PLAU (0.46) | PLAUCYP2A6F12NCF1NOS3 | |
| SCHEMBL28216191 | 0.87 | PLAU (0.44) | PLAUCYP2A6F12NCF1NOS3 | |
| Tetrahydrofuran SCHEMBL28212806 | 0.85 | PLAU (0.43) | PLAUCYP2A6F12NCF1NOS3 | |
| SCHEMBL21767613 | 0.83 | CYP3A4 (0.61) | PLAUCYP2A6F12NCF1NOS3 | |
| Isobutane SCHEMBL28383369 | 0.82 | RAB9A (0.47) | PLAUCYP2A6F12NCF1NOS3 | |
| Bicarbonate SCHEMBL29239049 | 0.81 | CYP2A6 (0.43) | PLAUCYP2A6F12NCF1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 609 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865932-B | Preparation method of benzothiophene sulfone compound with medicinal and fluorescent activity | BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-119080696-B | Preparation and application of multifunctional electroluminescent material with AIE property and reversible mechanochromism property | 海南师范大学 | 2025-05-02 | — | — | CN | claimed |
| CN-119841818-A | Carbazole derivative and preparation method and application thereof | 福建理工大学 | 2025-04-18 | — | — | CN | claimed |
| CN-119080696-A | Preparation and application of multifunctional electroluminescent material with AIE property and reversible mechanochromism property | 海南师范大学 | 2024-12-06 | — | — | CN | claimed |
| CN-117865932-A | Preparation method of benzothiophene sulfone compound with medicinal and fluorescent activity | 北京化工大学 | 2024-04-12 | — | — | CN | claimed |
| CN-113292494-A | Isoquinoline carboxylic acid compound and preparation method and application thereof | 江苏苏中药业集团股份有限公司 | 2021-08-24 | — | — | CN | claimed |
| CN-112047884-A | Synthesis method of 4-fluoroisoquinoline sulfate | 沈阳市摩尔医药技术开发有限责任公司 | 2020-12-08 | — | — | CN | claimed |
| CN-105384767-B | One kind is based on S, the polymer precursor monomer of S- dioxo-dibenzothiophene salt, polymer and the preparation method and application thereof | 华南理工大学 | 2019-01-15 | — | — | CN | claimed |
| CN-108084090-A | Synthetic method of brominated compound containing nitrogen heterocycle as drug intermediate | 北京六合宁远科技有限公司 | 2018-05-29 | — | — | CN | claimed |
| CN-105669547-A | Preparation method of 8-nitro-1,2,3,4-tetrahydroisoquinoline | 苏州大学 | 2016-06-15 | — | — | CN | claimed |
| CN-102812014-B | The purposes of novel 9 oxime derivate and the allosteric modulators as metabotropic glutamate receptor thereof | DOMAIN THERAPEUTICS (FR) | 2016-01-20 | — | — | CN | claimed |
| CN-102875465-A | Method for preparing 7-bromoisoquinoline | UNIV SHANGHAI | 2013-01-16 | — | — | CN | claimed |
| CN-101928943-B | Compound corrosion inhibitor for butyl rubber chloromethane glycol dehydrating regeneration system | CHINA PETROLEUM & CHEMICAL | 2013-01-16 | — | — | CN | claimed |
| CN-101928942-A | Composite corrosion inhibitor of butyl rubber chloromethane glycol dehydration regeneration system | CHINA PETROLEUM & CHEMICAL | 2010-12-29 | — | — | CN | claimed |
| CN-101928943-A | Compound corrosion inhibitor for butyl rubber chloromethane glycol dehydrating regeneration system | CHINA PETROLEUM & CHEMICAL | 2010-12-29 | — | — | CN | claimed |
| CN-117865932-B | Preparation method of benzothiophene sulfone compound with medicinal and fluorescent activity | BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY (CN) | 2026-05-26 | — | — | CN | disclosed |
| US-20260085073-A1 | PYRAZOLYLCARBOXAMIDE COMPOUNDS AND THEIR USE IN THERAPY | HOTSPOT THERAPEUTICS INC (US) | 2026-03-26 | — | — | US | disclosed |
| US-4855420-A | Cephalosporin derivatives | ICI PHARMA (FR) | 1989-08-08 | — | — | US | disclosed |
| US-4678781-A | BACTERICIDAL ANTIBIOTICS | ICI PHARMA (FR) | 1987-07-07 | — | — | US | disclosed |
| US-4122180-A | Isoquinolines and anti-depressants containing them | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1978-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260085073-A1 | PYRAZOLYLCARBOXAMIDE COMPOUNDS AND THEIR USE IN THERAPY | MALT1, BCL6, BCL3 | PLAU 4767/4885CYP2A6 707/4885F12 3873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.