Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 11/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24863530 | 0.90 | KLKB1 (0.37) | KLKB1RIPK1 | |
| SCHEMBL24863510 | 0.90 | KLKB1 (0.38) | KLKB1RIPK1PTGDR2 | |
| SCHEMBL25659921 | 0.88 | KLKB1 (0.42) | KLKB1 | |
| SCHEMBL25659890 | 0.88 | KLKB1 (0.41) | KLKB1 | |
| SCHEMBL31352671 | 0.87 | KLKB1 (0.42) | KLKB1MAPTPTGDR2 | |
| SCHEMBL24863505 | 0.87 | KLKB1 (0.43) | KLKB1MAPT | |
| SCHEMBL24863408 | 0.84 | KLKB1 (0.57) | KLKB1 | |
| SCHEMBL25660016 | 0.81 | KLKB1 (0.41) | KLKB1MAPTPTGDR2 | |
| SCHEMBL25659805 | 0.81 | KLKB1 (0.41) | KLKB1MAPT | |
| SCHEMBL25660357 | 0.79 | KLKB1 (0.42) | KLKB1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11814371-B2 | Heterocyclic compound | MEDSHINE DISCOVERY INC. (CN) | 2023-11-14 | — | — | US | disclosed |
| US-20230167098-A1 | HETEROCYCLIC COMPOUND | MEDSHINE DISCOVERY INC. (CN) | 2023-06-01 | — | — | US | disclosed |
| EP-4116299-A1 | HETEROCYCLIC COMPOUND | Medshine Discovery Inc. (CN) | 2023-01-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167098-A1 | HETEROCYCLIC COMPOUND | CYP11B2, CYP4F11, CYP11B1 | KLKB1 1724/4885RIPK1 4823/4885MAPT 3511/4885 |
| US-11814371-B2 | Heterocyclic compound | CYP11B2, CYP4F11, CYP11B1 | KLKB1 1724/4885RIPK1 4823/4885MAPT 3511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.