Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27291427 | 0.91 | MEN1 (0.32) | MEN1KMT2ALMNAL3MBTL1TDP1 | |
| SCHEMBL29343438 | 0.86 | LMNA (0.37) | LMNAL3MBTL1TDP1BLMPMP22 | |
| SCHEMBL29342248 | 0.86 | LMNA (0.37) | LMNAL3MBTL1TDP1BLMPMP22 | |
| SCHEMBL21483116 | 0.86 | LMNA (0.37) | LMNAL3MBTL1TDP1BLMPMP22 | |
| SCHEMBL24864388 | 0.86 | LMNA (0.37) | LMNAL3MBTL1TDP1BLMPMP22 | |
| SCHEMBL29337937 | 0.86 | LMNA (0.37) | LMNAL3MBTL1TDP1BLMPMP22 | |
| SCHEMBL24864627 | 0.86 | LMNA (0.37) | LMNAL3MBTL1TDP1BLMPMP22 | |
| SCHEMBL24864413 | 0.86 | LMNA (0.37) | LMNAL3MBTL1TDP1BLMPMP22 | |
| Hydrochloric Acid SCHEMBL21460762 | 0.85 | LMNA (0.35) | LMNAL3MBTL1TDP1BLMPMP22 | |
| Hydrochloric Acid SCHEMBL21460758 | 0.85 | LMNA (0.35) | LMNAL3MBTL1TDP1BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280227-A2 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2023-01-12 | — | — | WO | disclosed |