SCHEMBL2486470

SCHEMBL2486470

CCCCCCCCCCCCc1[c]ccc2c1CCO2

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 7/20 0.33
HTR2A P28223 5/20 0.33
HTR2B P41595 4/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33
CYP1A1 P04798 1/20 0.32
MTNR1B P49286 1/20 0.31
ESR1 P03372 2/20 0.30
ADRA2A P08913 2/20 0.30
ADORA3 P0DMS8 2/20 0.30
TACR2 P21452 2/20 0.30
SLC6A2 P23975 2/20 0.30
SLC6A4 P31645 2/20 0.30
SLC6A3 Q01959 2/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
SHBG P04278 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1472895 1.00 HTR2C (0.33) HTR2CHTR2AHTR2BMEN1KMT2A
SCHEMBL1483219 1.00 HTR2C (0.33) HTR2CHTR2AHTR2BMEN1KMT2A
SCHEMBL631761 1.00 HTR2C (0.33) HTR2CHTR2AHTR2BMEN1KMT2A
SCHEMBL9283980 0.98 HTR2C (0.34) HTR2CHTR2AHTR2BMEN1KMT2A
SCHEMBL7994704 0.75 CYP1A1 (0.33) CYP1A1
SCHEMBL11700447 0.75 CYP2D6 (0.34) HTR2CHTR2AMEN1KMT2AATM
SCHEMBL7644027 0.75 CYP2D6 (0.34) HTR2CHTR2AMEN1KMT2AATM
SCHEMBL7462090 0.75 CYP3A4 (0.33) HTR2CMEN1KMT2ACYP1A1ESR1
SCHEMBL8143277 0.73 CYP1A1 (0.35) HTR2CHTR2ACYP1A1ESR1ADRA2A
SCHEMBL6886568 0.73 AOC3 (0.34) CYP1A1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109843969-A Curing agent for aqueous epoxy resin, aqueous epoxy resin composition, and cured product thereof 三菱瓦斯化学株式会社 2019-06-04 CN disclosed
EP-1835351-B1 Toner, method of manufacturing the same, image forming apparatus, process cartridge and image forming method RICOH CO LTD (JP) 2011-09-07 EP disclosed
EP-2047337-A1 IMAGE FORMATION APPARATUS Ricoh Company, Ltd. (JP) 2009-04-15 EP disclosed
WO-2008013297-A1 IMAGE FORMATION APPARATUS RICOH COMPANY, LTD. (JP) 2008-01-31 WO disclosed
EP-1835351-A1 Toner, method of manufacturing the same, image forming apparatus, process cartridge and image forming method Ricoh Company, Ltd. (JP) 2007-09-19 EP disclosed
US-5277992-A Back coat layer with a kinetic friction coefficient SONY CORPORATION (JP) 1994-01-11 US disclosed