SCHEMBL8143277

SCHEMBL8143277

CCCCCCCCCc1[c]ccc2c1O2

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 1/20 0.35
KCNH2 Q12809 5/20 0.34
ESR1 P03372 2/20 0.34
ADRA2A P08913 2/20 0.34
ADORA3 P0DMS8 2/20 0.34
TACR2 P21452 2/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34
SLC6A3 Q01959 2/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
SHBG P04278 1/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
HSPD1 P10809 1/20 0.34
ADRB3 P13945 1/20 0.34
HTR2C P28335 1/20 0.34
HSPE1 P61604 1/20 0.34
HIF1A Q16665 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7462090 0.81 CYP3A4 (0.33) CYP1A1ESR1ADRA2AADORA3TACR2
SCHEMBL6886568 0.79 AOC3 (0.34) CYP1A1ALDH1A1CYP3A4TRPV1
SCHEMBL4847880 0.75 PTGS2 (0.40) KCNH2ESR1ADRA2AADORA3TACR2
SCHEMBL4851247 0.75 PTGS2 (0.40) KCNH2ESR1ADRA2AADORA3TACR2
SCHEMBL4851680 0.75 PTGS2 (0.40) KCNH2ESR1ADRA2AADORA3TACR2
SCHEMBL4849582 0.75 PTGS2 (0.40) KCNH2ESR1ADRA2AADORA3TACR2
SCHEMBL4844580 0.75 PTGS2 (0.40) KCNH2ESR1ADRA2AADORA3TACR2
SCHEMBL4847847 0.75 PTGS2 (0.40) KCNH2ESR1ADRA2AADORA3TACR2
SCHEMBL4844673 0.75 PTGS2 (0.40) KCNH2ESR1ADRA2AADORA3TACR2
SCHEMBL4846766 0.75 PTGS2 (0.40) KCNH2ESR1ADRA2AADORA3TACR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6090487-A COMPOSITION WHICH REACTS TO ULTRAVIOLET RADIATION OR TO ELECTRON BEAM; COMPOSITES VETROTEX FRANCE (FR) 2000-07-18 US disclosed
US-5882792-A Sizing composition for glass threads, process using this composition and resulting products VETROTEX FRANCE (FR) 1999-03-16 US disclosed