SCHEMBL24865067

SCHEMBL24865067

Cn1c(=O)c(C(=O)c2ccc(N(c3ccccc3)c3cccc4ccccc34)cc2)c(O)c2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 7/20 0.56
▸ MEN1 O00255 6/20 0.56
▸ PGR P06401 1/20 0.56
▸ ALDH1A1 P00352 5/20 0.51
▸ KDM4E B2RXH2 4/20 0.48
▸ GAA P10253 1/20 0.47
▸ NPC1 O15118 4/20 0.47
▸ RAB9A P51151 3/20 0.47
▸ NLRP3 Q96P20 2/20 0.45
▸ L3MBTL1 Q9Y468 2/20 0.45
▸ ALOX15 P16050 1/20 0.45
▸ NPSR1 Q6W5P4 2/20 0.43
▸ LMNA P02545 2/20 0.43
▸ TP53 P04637 1/20 0.43
▸ HPGD P15428 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24864731 0.89 KMT2A (0.65) KMT2AMEN1PGRALDH1A1KDM4E
SCHEMBL30171504 0.85 KMT2A (0.61) KMT2AMEN1PGRALDH1A1KDM4E
SCHEMBL27212350 0.85 KMT2A (0.61) KMT2AMEN1PGRALDH1A1KDM4E
SCHEMBL30804603 0.83 ALDH1A1 (0.59) KMT2AMEN1PGRALDH1A1KDM4E
SCHEMBL27212336 0.83 ALDH1A1 (0.59) KMT2AMEN1PGRALDH1A1KDM4E
SCHEMBL24865025 0.81 KMT2A (0.59) KMT2AMEN1PGRALDH1A1KDM4E
SCHEMBL24864976 0.80 ALDH1A1 (0.72) KMT2AMEN1PGRALDH1A1KDM4E
SCHEMBL30804578 0.80 ALDH1A1 (0.72) KMT2AMEN1PGRALDH1A1KDM4E
Water SCHEMBL30804585 0.78 ALDH1A1 (0.68) KMT2AMEN1PGRALDH1A1KDM4E
SCHEMBL24864974 0.75 KMT2A (0.66) KMT2AMEN1PGRALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250074925-A1 RARE EARTH COMPLEX SAGAMI CHEMICAL RESEARCH INSTITUTE (JP) 2025-03-06 — — US disclosed
EP-4365180-A1 RARE EARTH COMPLEX Tosoh Corporation (JP) 2024-05-08 — — EP disclosed
WO-2023282236-A1 RARE EARTH COMPLEX 東ソー株式会社 2023-01-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250074925-A1 RARE EARTH COMPLEX L1CAM, CHRM1, NPM1 KMT2A 3223/4885MEN1 140/4885PGR 1646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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