Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.43 |
| ▸ | FLT3 | P36888 | 2/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | UGCG | Q16739 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | PRF1 | P14222 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30885148 | 1.00 | KIT (0.43) | KITFLT3MKNK1KDM4EPIK3CA | |
| SCHEMBL24865715 | 0.92 | DDB1 (0.42) | KITFLT3KDM4ENPC1RAB9A | |
| SCHEMBL30885145 | 0.92 | DDB1 (0.42) | KITFLT3KDM4ENPC1RAB9A | |
| SCHEMBL24865233 | 0.87 | KIT (0.41) | KITFLT3MKNK1 | |
| SCHEMBL24865514 | 0.86 | KIT (0.44) | KITFLT3MKNK1PIK3CAMTOR | |
| SCHEMBL30336555 | 0.82 | KIT (0.43) | KITFLT3MKNK1PIK3CAMTOR | |
| SCHEMBL24865685 | 0.82 | KIT (0.43) | KITFLT3MKNK1PIK3CAMTOR | |
| SCHEMBL24865651 | 0.78 | DDB1 (0.44) | KITFLT3MKNK1BRD4 | |
| SCHEMBL24865585 | 0.78 | MKNK1 (0.41) | KITFLT3MKNK1PIK3CAMTOR | |
| SCHEMBL24865537 | 0.78 | KIT (0.43) | KITFLT3MKNK1PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |