Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.43 |
| ▸ | FLT3 | P36888 | 2/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | BCL6 | P41182 | 2/20 | 0.36 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 4/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | UGCG | Q16739 | 3/20 | 0.33 |
| ▸ | PRF1 | P14222 | 1/20 | 0.33 |
| ▸ | WEE1 | P30291 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30336555 | 1.00 | KIT (0.43) | KITFLT3MKNK1PIK3CAMTOR | |
| SCHEMBL24865537 | 0.95 | KIT (0.43) | KITFLT3MKNK1PIK3CAMTOR | |
| SCHEMBL30336441 | 0.95 | KIT (0.43) | KITFLT3MKNK1PIK3CAMTOR | |
| SCHEMBL24865514 | 0.94 | KIT (0.44) | KITFLT3MKNK1PIK3CAMTOR | |
| SCHEMBL24865651 | 0.85 | DDB1 (0.44) | KITFLT3MKNK1BCL6DDB1 | |
| SCHEMBL30885148 | 0.82 | KIT (0.43) | KITFLT3MKNK1PIK3CAMTOR | |
| SCHEMBL24865331 | 0.82 | KIT (0.43) | KITFLT3MKNK1PIK3CAMTOR | |
| SCHEMBL24865372 | 0.82 | MKNK1 (0.44) | KITFLT3MKNK1PIK3CAMTOR | |
| SCHEMBL24865396 | 0.82 | MKNK1 (0.42) | KITFLT3MKNK1PIK3CAMTOR | |
| SCHEMBL30336295 | 0.82 | MKNK1 (0.42) | KITFLT3MKNK1PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |