Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | BCL6 | P41182 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30336295 | 1.00 | MKNK1 (0.42) | MKNK1PIK3CAMTORKITFLT3 | |
| SCHEMBL24865372 | 0.87 | MKNK1 (0.44) | MKNK1PIK3CAMTORKITFLT3 | |
| SCHEMBL30336441 | 0.85 | KIT (0.43) | MKNK1PIK3CAMTORKITFLT3 | |
| SCHEMBL24865537 | 0.85 | KIT (0.43) | MKNK1PIK3CAMTORKITFLT3 | |
| SCHEMBL30336349 | 0.85 | MKNK1 (0.47) | MKNK1PIK3CAMTORKITFLT3 | |
| SCHEMBL24865076 | 0.85 | MKNK1 (0.47) | MKNK1PIK3CAMTORKITFLT3 | |
| SCHEMBL30336555 | 0.82 | KIT (0.43) | MKNK1PIK3CAMTORKITFLT3 | |
| SCHEMBL24865685 | 0.82 | KIT (0.43) | MKNK1PIK3CAMTORKITFLT3 | |
| SCHEMBL24865245 | 0.80 | MKNK1 (0.42) | MKNK1PIK3CAMTORKITFLT3 | |
| SCHEMBL30336087 | 0.80 | MKNK1 (0.42) | MKNK1PIK3CAMTORKITFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |