Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | BRD2 | P25440 | 1/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.40 |
| ▸ | BCL6 | P41182 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 2/20 | 0.32 |
| ▸ | CCND1 | P24385 | 2/20 | 0.32 |
| ▸ | CCND2 | P30279 | 2/20 | 0.32 |
| ▸ | CCND3 | P30281 | 2/20 | 0.32 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31123328 | 1.00 | BRD4 (0.45) | BRD4BRD2BRD3BCL6CNR2 | |
| SCHEMBL24865338 | 0.84 | TRIM24 (0.42) | BRD4BCL6CNR2SYKEGFR | |
| SCHEMBL24865619 | 0.83 | BCL6 (0.36) | BRD4BCL6CNR2SYKDCLK1 | |
| SCHEMBL24865514 | 0.83 | KIT (0.44) | BCL6CNR2SYK | |
| SCHEMBL31123249 | 0.82 | CNR2 (0.36) | BRD4BCL6CNR2SYKDCLK1 | |
| SCHEMBL24865354 | 0.82 | CNR2 (0.36) | BRD4BCL6CNR2SYKDCLK1 | |
| SCHEMBL24865525 | 0.82 | BCL6 (0.35) | BCL6CNR2SYKDCLK1LRRK2 | |
| SCHEMBL24865651 | 0.81 | DDB1 (0.44) | BRD4BCL6CNR2DCLK1LRRK2 | |
| SCHEMBL31123277 | 0.80 | CNR2 (0.36) | BCL6CNR2SYKSCN10AEGFR | |
| SCHEMBL24865078 | 0.79 | KIT (0.33) | BRD4BCL6CNR2EGFRJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |