Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865767 | 0.83 | SYK (0.38) | MAPTALDH1A1KMT2AGAAKDM4E | |
| SCHEMBL14431554 | 0.78 | CYP1A2 (0.58) | MAPTALDH1A1KMT2AGAAKDM4E | |
| SCHEMBL24865085 | 0.78 | SMN1; SMN2 (0.43) | MAPTALDH1A1KMT2AGAAKDM4E | |
| SCHEMBL24865762 | 0.77 | NPC1 (0.33) | MAPTALDH1A1KMT2AGAAKDM4E | |
| SCHEMBL2174874 | 0.77 | MAPT (0.58) | MAPTALDH1A1KMT2AGAAKDM4E | |
| SCHEMBL1916616 | 0.75 | CYP1A2 (0.59) | MAPTALDH1A1KMT2AGAAKDM4E | |
| SCHEMBL7343928 | 0.73 | MAPT (0.56) | MAPTALDH1A1KMT2AGAAKDM4E | |
| SCHEMBL30885108 | 0.73 | LMNA (0.59) | MAPTALDH1A1KMT2AGAAKDM4E | |
| SCHEMBL17361558 | 0.73 | MAPT (0.53) | MAPTALDH1A1KMT2AGAAKDM4E | |
| SCHEMBL11726654 | 0.72 | NPC1 (0.58) | MAPTALDH1A1KMT2AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |