Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | BRD1 | O95696 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31123320 | 1.00 | BCL6 (0.39) | BCL6SMN1; SMN2TP53PKMHSD17B10 | |
| SCHEMBL24865227 | 0.93 | BCL6 (0.38) | BCL6SMN1; SMN2TP53PKMHSD17B10 | |
| SCHEMBL30336449 | 0.93 | BCL6 (0.38) | BCL6SMN1; SMN2TP53PKMHSD17B10 | |
| SCHEMBL24865744 | 0.91 | BCL6 (0.40) | BCL6SMN1; SMN2TP53HSD17B10ALDH1A1 | |
| SCHEMBL30336382 | 0.84 | GAA (0.46) | SMN1; SMN2TP53PKMHSD17B10ALDH1A1 | |
| SCHEMBL24865630 | 0.84 | GAA (0.46) | SMN1; SMN2TP53PKMHSD17B10ALDH1A1 | |
| SCHEMBL30336323 | 0.84 | ALDH1A1 (0.45) | BCL6SMN1; SMN2TP53PKMHSD17B10 | |
| SCHEMBL24865579 | 0.84 | ALDH1A1 (0.45) | BCL6SMN1; SMN2TP53PKMHSD17B10 | |
| SCHEMBL24865509 | 0.83 | SMN1; SMN2 (0.42) | BCL6SMN1; SMN2TP53PKMHSD17B10 | |
| SCHEMBL24865649 | 0.81 | ALDH1A1 (0.48) | BCL6SMN1; SMN2TP53HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |