Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30336544 | 1.00 | BCL6 (0.42) | BCL6CNR2GAASMN1; SMN2BRD4 | |
| SCHEMBL24865459 | 0.88 | BCL6 (0.46) | BCL6CNR2GAASMN1; SMN2MAPT | |
| SCHEMBL30885111 | 0.88 | BCL6 (0.46) | BCL6CNR2GAASMN1; SMN2MAPT | |
| SCHEMBL24865299 | 0.88 | BCL6 (0.50) | BCL6CNR2GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL31123270 | 0.88 | BCL6 (0.50) | BCL6CNR2GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL24865687 | 0.86 | BCL6 (0.41) | BCL6CNR2GAASMN1; SMN2FYN | |
| SCHEMBL29208996 | 0.86 | BCL6 (0.41) | BCL6CNR2GAASMN1; SMN2FYN | |
| SCHEMBL30336115 | 0.85 | SMN1; SMN2 (0.43) | GAASMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL24865638 | 0.85 | SMN1; SMN2 (0.43) | GAASMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL24865755 | 0.79 | EGFR (0.40) | BCL6CNR2GAAEGFRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |