Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | GAA | P10253 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30336115 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1LMNAUSP2RAB9A | |
| SCHEMBL24865209 | 0.87 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1LMNAUSP2RAB9A | |
| SCHEMBL30336497 | 0.87 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1LMNAUSP2RAB9A | |
| SCHEMBL30336544 | 0.85 | BCL6 (0.42) | SMN1; SMN2ALDH1A1LMNAMAPTGAA | |
| SCHEMBL24865669 | 0.85 | BCL6 (0.42) | SMN1; SMN2ALDH1A1LMNAMAPTGAA | |
| SCHEMBL24865676 | 0.77 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1LMNAUSP2RAB9A | |
| SCHEMBL24865656 | 0.77 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1LMNAGAAMEN1 | |
| SCHEMBL24865664 | 0.77 | EGFR (0.53) | SMN1; SMN2ALDH1A1LMNAUSP2RAB9A | |
| SCHEMBL24865238 | 0.76 | GABRG2 (0.46) | SMN1; SMN2ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL31123236 | 0.76 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1LMNAUSP2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |