Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 12/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.36 |
| ▸ | PARG | Q86W56 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31123214 | 1.00 | BCL6 (0.49) | BCL6NCOR2PARGJAK2GAA | |
| SCHEMBL24865674 | 0.87 | BCL6 (0.49) | BCL6NCOR2PARG | |
| SCHEMBL31123223 | 0.87 | BCL6 (0.49) | BCL6NCOR2PARG | |
| SCHEMBL31123270 | 0.86 | BCL6 (0.50) | BCL6GAASMN1; SMN2CNR2 | |
| SCHEMBL24865299 | 0.86 | BCL6 (0.50) | BCL6GAASMN1; SMN2CNR2 | |
| SCHEMBL24865470 | 0.84 | BCL6 (0.48) | BCL6NCOR2PARGADRB3HTR1D | |
| SCHEMBL31123201 | 0.84 | BCL6 (0.48) | BCL6NCOR2PARGADRB3HTR1D | |
| SCHEMBL24864837 | 0.83 | BCL6 (0.38) | BCL6JAK2CNR2 | |
| SCHEMBL24865124 | 0.83 | BCL6 (0.53) | BCL6NCOR2ADRB3HTR1DADORA1 | |
| SCHEMBL31123241 | 0.83 | BCL6 (0.53) | BCL6NCOR2ADRB3HTR1DADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |