SCHEMBL24866176

SCHEMBL24866176

COc1ccc(N2CCN(C)CC2)cc1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12

nearest known ligand 0.75

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ KAT6A Q92794 20/20 0.75
▸ KAT7 O95251 19/20 0.75
▸ KAT6B Q8WYB5 16/20 0.75
▸ KAT5 Q92993 16/20 0.75
▸ KAT8 Q9H7Z6 16/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24866175 0.94 KAT6A (0.77) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL24866190 0.92 KAT6A (0.75) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL24866151 0.88 KAT6A (0.77) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL22802424 0.86 KAT6A (1.00) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL22817446 0.86 KAT7 (1.00) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL22817329 0.86 KAT7 (1.00) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL30680851 0.86 KAT6A (0.69) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL26969659 0.86 KAT6A (0.69) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL22802508 0.85 KAT7 (0.83) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL30680835 0.85 KAT7 (0.83) KAT6AKAT7KAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023280182-A1 COMPOUND SERVING AS KAT6 INHIBITOR 杭州英创医药科技有限公司 2023-01-12 — — WO disclosed
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