SCHEMBL30680851

SCHEMBL30680851

COc1ccc(N2CC3(CCNCC3)C2)cc1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12

nearest known ligand 0.69

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ KAT6A Q92794 20/20 0.69
▸ KAT7 O95251 19/20 0.69
▸ KAT6B Q8WYB5 16/20 0.69
▸ KAT5 Q92993 16/20 0.69
▸ KAT8 Q9H7Z6 16/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26969659 1.00 KAT6A (0.69) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL30680845 0.90 KAT7 (0.69) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL26969632 0.90 KAT7 (0.69) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL26969664 0.88 KAT7 (0.64) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL30680829 0.88 KAT7 (0.64) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL24866175 0.87 KAT6A (0.77) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL30680841 0.86 KAT7 (0.69) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL26969649 0.86 KAT7 (0.69) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL24866176 0.86 KAT6A (0.75) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL24866190 0.86 KAT6A (0.75) KAT6AKAT7KAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4539937-A1 KAT6 TARGETING COMPOUNDS WITH UBIQUITIN LIGASE BINDING MOIETY Prelude Therapeutics Incorporated (US) 2025-04-23 — — EP disclosed
WO-2023245150-A9 KAT6 TARGETING COMPOUNDS WITH UBIQUITIN LIGASE BINDING MOIETY PRELUDE THERAPEUTICS INCORPORATED (US) 2025-01-16 — — WO disclosed
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