SCHEMBL24866764

SCHEMBL24866764

COc1cc(C#Cc2cccnc2)cc(OC)c1SNc1noc2cc(Cn3cccn3)cc(OC)c12

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ KAT7 O95251 20/20 0.53
▸ KAT6A Q92794 20/20 0.53
▸ KAT6B Q8WYB5 14/20 0.53
▸ KAT5 Q92993 14/20 0.53
▸ KAT8 Q9H7Z6 14/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24866485 0.95 KAT7 (0.52) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL24866749 0.89 KAT7 (0.57) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL24866482 0.85 KAT6A (0.54) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22817402 0.85 KAT7 (0.68) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL24866200 0.85 KAT7 (0.74) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL24866460 0.84 KAT6A (0.51) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL24866228 0.83 KAT6A (0.50) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL24866189 0.82 KAT6A (0.74) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL24866174 0.82 KAT6A (0.49) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL24866202 0.82 KAT7 (0.71) KAT7KAT6AKAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023280182-A1 COMPOUND SERVING AS KAT6 INHIBITOR 杭州英创医药科技有限公司 2023-01-12 — — WO disclosed
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