SCHEMBL2486689

SCHEMBL2486689

CCCCCCc1cccc(-c2ccccn2)c1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP19A1 P11511 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
HRH3 Q9Y5N1 1/20 0.49
TGFBR1 P36897 1/20 0.47
LPL P06858 2/20 0.47
LIPG Q9Y5X9 2/20 0.47
SPHK2 Q9NRA0 1/20 0.46
FFAR1 O14842 1/20 0.45
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
PPARG P37231 1/20 0.44
PPARA Q07869 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16203116 0.97 CYP1A2 (0.48) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL2481791 0.96 CYP1A2 (0.50) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL22387811 0.94 CYP1A2 (0.53) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL16353200 0.90 CYP1A2 (0.47) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL4472579 0.88 HRH3 (0.54) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL16203117 0.87 CYP1A2 (0.50) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL16133093 0.87 HRH3 (0.50) HRH3TGFBR1FFAR1
SCHEMBL16203115 0.87 FFAR1 (0.52) HRH3FFAR1
SCHEMBL16203110 0.87 FFAR1 (0.52) HRH3FFAR1
SCHEMBL16133092 0.85 HRH3 (0.49) HRH3TGFBR1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1424350-B1 PHOSPHOR LIGHT-EMITTING COMPOUND, PHOSPHOR LIGHT-EMITTING COMPOSITION, AND ORGANIC LIGHT EMITTING ELEMENT JAPAN BROADCASTING CORP (JP) 2014-08-27 EP disclosed
EP-2154165-B1 A phosphorescent compound, a phosphorescent composition and an organic light-emitting device JAPAN BROADCASTING CORP (JP) 2011-10-19 EP disclosed
EP-2159237-A1 PHOSPHOR LIGHT-EMITTING COMPOSITION AND ORGANIC LIGHT EMITTING ELEMENT Nippon Hoso Kyokai (JP) 2010-03-03 EP disclosed
EP-2154165-A1 A phosphorescent compound, a phosphorescent composition and an organic light-emitting device Nippon Hoso Kyokai (JP) 2010-02-17 EP disclosed
CN-100487008-C Phosphorescent compound, a phosphorescent composition and an organic light-emitting device JAPAN BROADCASTING CORP SHOWA (JP) 2009-05-13 CN disclosed
US-7250226-B2 Organic polymeric phosphorescent compound of an unsaturated metal complex NIPPON HOSO KYOKAI (JP) 2007-07-31 US disclosed
CN-1547597-A Phosphorescent compound, a phosphorescent composition and an organic light-emitting device �ձ�����Э�� 2004-11-17 CN disclosed
EP-1424350-A1 PHOSPHOR LIGHT−EMITTING COMPOUND, PHOSPHOR LIGHT−EMITTING COMPOSITION, AND ORGANIC LIGHT EMITTING ELEMENT NIPPON HOSO KYOKAI (JP) 2004-06-02 EP disclosed
US-20030091862-A1 Phosphorescent compound, a phosphorescent composition and an organic light-emitting device NIPPON HOSO KYOKAI 2003-05-15 US disclosed