Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 3/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22387811 | 0.90 | CYP1A2 (0.53) | HRH3CTSSCTSKFFAR1CYP1A2 | |
| SCHEMBL2486689 | 0.88 | CYP1A2 (0.50) | HRH3FFAR1CYP1A2CYP2D6CYP19A1 | |
| SCHEMBL8270139 | 0.86 | HRH3 (0.56) | HRH3CTSSCTSKFFAR1CYP1A2 | |
| SCHEMBL20200083 | 0.86 | FFAR1 (0.58) | HRH3CTSSFFAR1CYP1A2TGFBR1 | |
| SCHEMBL3779112 | 0.86 | CYP1A2 (0.48) | HRH3FFAR1CYP1A2CYP2D6CYP19A1 | |
| SCHEMBL16203116 | 0.85 | CYP1A2 (0.48) | HRH3FFAR1CYP1A2CYP2D6CYP19A1 | |
| SCHEMBL2481791 | 0.84 | CYP1A2 (0.50) | HRH3FFAR1CYP1A2CYP2D6CYP19A1 | |
| SCHEMBL5266894 | 0.83 | HRH3 (0.54) | HRH3FFAR1CYP1A2TGFBR1CYP2A6 | |
| SCHEMBL1139044 | 0.83 | HRH3 (0.57) | HRH3CTSSFFAR1CYP1A2TGFBR1 | |
| SCHEMBL1138657 | 0.83 | HRH3 (0.54) | HRH3CTSSFFAR1CYP1A2TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101835745-B | Method for producing disulfonic acid compound, asymmetric mannich catalyst, method for producing beta-aminocarbonyl derivative, and disulfonate salt | UNIV NAGOYA NAT UNIV CORP | 2013-08-28 | — | — | CN | disclosed |
| US-20120108566-A1 | NICOTINAMIDES AS JAK KINASE MODULATORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2012-05-03 | — | — | US | disclosed |
| CN-101835745-A | Method for producing disulfonic acid compound, asymmetric mannich catalyst, method for producing beta-aminocarbonyl derivative, and novel disulfonate | UNIV NAGOYA NAT UNIV CORP | 2010-09-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108566-A1 | NICOTINAMIDES AS JAK KINASE MODULATORS | JAK2, JAK1, NADK | HRH3 1134/4885CTSS 3506/4885CTSK 2136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.