Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 18/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.41 |
| ▸ | TTK | P33981 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24866936 | 0.88 | VNN1 (0.44) | PTK2 | |
| SCHEMBL24866940 | 0.88 | VNN1 (0.40) | PTK2 | |
| SCHEMBL24867185 | 0.84 | VNN1 (0.43) | LRRK2 | |
| SCHEMBL24866939 | 0.84 | VNN1 (0.41) | PTK2 | |
| SCHEMBL24867300 | 0.83 | PDE4A (0.42) | LRRK2TTK | |
| SCHEMBL24867191 | 0.77 | VNN1 (0.38) | — | |
| SCHEMBL24867186 | 0.75 | KDM4C (0.37) | LRRK2 | |
| SCHEMBL24866949 | 0.74 | VNN1 (0.41) | LRRK2 | |
| SCHEMBL24867239 | 0.74 | MAPT (0.38) | LRRK2PTK2TTK | |
| SCHEMBL24867180 | 0.72 | VNN1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283488-A9 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CZ BIOHUB SF, LLC (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023283488-A2 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CHAN ZUCKERBERG BIOHUB, INC. (US) | 2023-01-12 | — | — | WO | disclosed |