Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | WEE1 | P30291 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24866856 | 0.86 | MAP4K1 (0.45) | NAMPTLMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL24866850 | 0.82 | MAP4K1 (0.45) | NPY5RPTGS1PTGS2MAP4K1 | |
| SCHEMBL24867253 | 0.81 | NPY5R (0.38) | NAMPTLMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL24867251 | 0.79 | CHEK1 (0.39) | NAMPTLMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL24867227 | 0.79 | KCNH2 (0.41) | NAMPTLMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL24866854 | 0.78 | PDE10A (0.47) | NAMPTKDR | |
| SCHEMBL24867241 | 0.78 | CHEK1 (0.38) | NAMPTLMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL24867297 | 0.76 | PTGS1 (0.45) | HTTPTGS1PTGS2 | |
| SCHEMBL24867207 | 0.76 | SCN5A (0.46) | HRH3MAP4K1 | |
| SCHEMBL22452590 | 0.73 | NPY5R (0.48) | NAMPTLMNATSHRHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283488-A9 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CZ BIOHUB SF, LLC (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023283488-A2 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CHAN ZUCKERBERG BIOHUB, INC. (US) | 2023-01-12 | — | — | WO | disclosed |