⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18774980 | 0.77 | GRN (0.32) | — | |
| SCHEMBL18774981 | 0.76 | TDP1 (0.34) | — | |
| SCHEMBL18135528 | 0.76 | — | — | |
| SCHEMBL24867442 | 0.74 | GRIN2D (0.31) | — | |
| SCHEMBL16018401 | 0.74 | — | — | |
| SCHEMBL25847823 | 0.74 | MAPK1 (0.43) | — | |
| SCHEMBL22475169 | 0.73 | RNPEP (0.34) | — | |
| SCHEMBL26504177 | 0.73 | CHRNB2 (0.32) | — | |
| SCHEMBL906205 | 0.71 | TET2 (0.31) | — | |
| SCHEMBL17173862 | 0.71 | USP2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230008433-A1 | Inhibitors of SARM1 | DISARM THERAPEUTICS, INC. | 2023-01-12 | — | — | US | disclosed |