SCHEMBL248674

SCHEMBL248674

Nc1cc(Cl)ncc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38657136 1.00
SCHEMBL22465749 0.81
SCHEMBL29479539 0.77
SCHEMBL191846 0.77
SCHEMBL30780302 0.77 KMT2A (0.34)
SCHEMBL6307027 0.75
SCHEMBL30097067 0.75
SCHEMBL13016652 0.75
SCHEMBL191637 0.75
SCHEMBL29801557 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025049604-A1 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF MAZE THERAPEUTICS, INC. (US) 2025-03-06 WO claimed
US-12590102-B2 Compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2026-03-31 US disclosed
EP-4695256-A2 ERBB2 INHIBITORS Cogent Biosciences, Inc. (US) 2026-02-18 EP disclosed
US-20260028365-A1 TYROSINE KINASE 2 INHIBITORS AND USES THEREOF BIOGEN MA INC (US) 2026-01-29 US disclosed
WO-2025235874-A1 HETEROCYCLICS AS EGFR INHIBITORS SCHRÖDINGER, INC. (US) 2025-11-13 WO disclosed
EP-4615581-A2 FUSED MULTICYCLIC COMPOUNDS AND THEIR USE AS PARP1 INHIBITORS Laekna Pharmaceutical Ningbo Co., Ltd. (CN) 2025-09-17 EP disclosed
US-12384777-B2 Compounds comprising N-methyl-2-pyridone, and pharmaceutically acceptable salts Tay Therapeutics Limited (GB) 2025-08-12 US disclosed
EP-4554938-A1 TYROSINE KINASE 2 INHIBITORS AND USES THEREOF Biogen MA Inc. (US) 2025-05-21 EP disclosed
CN-119894879-A Tyrosine kinase 2 inhibitors and uses thereof 渤健马萨诸塞州股份有限公司 2025-04-25 CN disclosed
CN-119768400-A Fused ring compound, application thereof and pharmaceutical composition containing fused ring compound 苏州信诺维医药科技股份有限公司 2025-04-04 CN disclosed
US-20100261707-A9 THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES NV REMYND (BE) 2010-10-14 US disclosed
EP-1694677-B1 SPIROPIPERIDINE DERIVATIVES FOR CONTROLLING PESTS SYNGENTA PARTICIPATIONS AG (CH) 2009-12-02 EP disclosed
CN-101544640-A Spiropiperidine derivatives for controlling pests SYNGENTA PARTICIPATIONS AG 2009-09-30 CN disclosed
US-20090233911-A2 THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES NV REMYND (BE) 2009-09-17 US disclosed
US-20090054410-A1 THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES NV REMYND (BE) 2009-02-26 US disclosed
WO-2007089512-A1 GLUCOKINASE ACTIVATORS ARRAY BIOPHARMA INC. (US) 2007-08-09 WO disclosed
US-20070135408-A1 Spiropiperidine derivatives for controlling pests SYNGENTA CROP PROTECTION, INC. 2007-06-14 US disclosed
CN-1894249-A Spiropiperidine derivatives for controlling pests SYNGENTA PARTICIPATIONS AG (CH) 2007-01-10 CN disclosed
EP-1694677-A1 SPIROPIPERIDINE DERIVATIVES FOR CONTROLLING PESTS Syngenta Participations AG (CH) 2006-08-30 EP disclosed
WO-2005061500-A1 SPIROPIPERIDINE DERIVATIVES FOR CONTROLLING PESTS SYNGENTA PARTICIPATIONS AG (CH) 2005-07-07 WO disclosed