⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4532908 | 0.80 | KDM4E (0.67) | — | |
| SCHEMBL165337 | 0.78 | — | — | |
| SCHEMBL2169512 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL5744190 | 0.76 | — | — | |
| SCHEMBL166576 | 0.76 | — | — | |
| SCHEMBL27396299 | 0.76 | — | — | |
| SCHEMBL1162994 | 0.76 | — | — | |
| SCHEMBL31504724 | 0.76 | — | — | |
| SCHEMBL247550 | 0.76 | — | — | |
| Water SCHEMBL27535040 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104003984-B | Thiazole-4-formyl piperazine derivative and preparation method thereof and application | SHANDONG UNIVERSITY (CN) | 2016-03-02 | — | — | CN | claimed |
| CN-104016944-A | N-(2-(aminomethyl)phenyl)thiazolyl-4-formamide derivatives, and preparation method and application thereof | UNIV SHANDONG | 2014-09-03 | — | — | CN | claimed |
| CN-104003984-A | Thiazole-4-formyl piperazine derivative and preparing method and application thereof | UNIV SHANDONG | 2014-08-27 | — | — | CN | claimed |
| US-20260125356-A1 | TREATMENT OF LEISHMANIASIS | THE UNIV OF DURHAM (GB) | 2026-05-07 | — | — | US | disclosed |
| EP-4638436-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2025-10-29 | — | — | EP | disclosed |
| EP-4605086-A1 | TREATMENT OF LEISHMANIASIS | The University of Durham (GB) | 2025-08-27 | — | — | EP | disclosed |
| US-20250243177-A1 | sGC STIMULATORS | CYCLERION THERAPEUTICS, INC. | 2025-07-31 | — | — | US | disclosed |
| WO-2025098545-A1 | NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ) | 2025-05-15 | — | — | WO | disclosed |
| EP-4553080-A1 | NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES | Ustav Organicke Chemie a Biochemie AV CR, v.v.i. (CZ) | 2025-05-14 | — | — | EP | disclosed |
| US-20240254118-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES, INC. | 2024-08-01 | — | — | US | disclosed |
| WO-2024137852-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| US-4011236-A | N-(BENZIMIDAZOL-2-YL)ARYLCARBOXAMIDES AS ULTRAVIOLET (UV) LIGHT ABSORBERS | MERCK & CO., INC. (US) | 1977-03-08 | — | — | US | disclosed |
| US-4009164-A | Novel 2-substituted-1,2,4-thiadiazole-[2,3-a]-benzimidazoles and process for their preparation | SYNTEX (U.S.A.) INC. (US) | 1977-02-22 | — | — | US | disclosed |
| US-4003909-A | [(1,2,4-Oxadiazol-3-yl)phenyl]carbamic or thiocarbamic acid esters | E. R. SQUIBB & SONS, INC. (US) | 1977-01-18 | — | — | US | disclosed |
| US-4001237-A | HYPOTENSIVES | BRISTOL-MYERS COMPANY (US) | 1977-01-04 | — | — | US | disclosed |
| US-3985740-A | THERAPEUTIC AND ANTIBACTERIAL AGENTS | BRISTOL-MYERS COMPANY (US) | 1976-10-12 | — | — | US | disclosed |
| US-3979404-A | FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1976-09-07 | — | — | US | disclosed |
| US-3976654-A | FUNGICIDE | SYNTEX (U.S.A.) INC. (US) | 1976-08-24 | — | — | US | disclosed |
| US-3947413-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1976-03-30 | — | — | US | disclosed |
| US-3946031-A | FUNGICIDES | SYNTEX INC. (US) | 1976-03-23 | — | — | US | disclosed |