Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2737236 | 0.86 | RECQL (0.56) | RECQLGAAHDAC1SMN1; SMN2HDAC3 | |
| SCHEMBL24869068 | 0.85 | RECQL (0.55) | RECQLSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL11795645 | 0.81 | GAA (0.47) | GAAMEN1POLBKMT2ARAB9A | |
| SCHEMBL13773264 | 0.81 | KMT2A (0.50) | GAAKMT2A | |
| SCHEMBL10094403 | 0.81 | PARP14 (0.53) | RECQLGAASMN1; SMN2RAB9AKDM4E | |
| SCHEMBL520235 | 0.79 | GAA (0.46) | GAAHDAC1HDAC3HDAC2POLB | |
| SCHEMBL24869072 | 0.79 | NLRP3 (0.54) | RECQLSMN1; SMN2POLBRAB9AALDH1A1 | |
| SCHEMBL24869050 | 0.78 | RECQL (0.46) | RECQL | |
| SCHEMBL8955980 | 0.78 | SMN1; SMN2 (0.55) | GAAHDAC1SMN1; SMN2HDAC3HDAC2 | |
| SCHEMBL30748254 | 0.78 | SMN1; SMN2 (0.55) | GAAHDAC1SMN1; SMN2HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023279986-A1 | SIX-MEMBERED ARYL OR HETEROARYL AMIDES, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |