Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 16/20 | 0.61 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.59 |
| ▸ | MET | P08581 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphine SCHEMBL25950504 | 0.87 | MAP4K1 (0.63) | MAP4K1ALKMET | |
| Phosphine SCHEMBL25950522 | 0.86 | MAP4K1 (0.64) | MAP4K1ALKMET | |
| Phosphine SCHEMBL25950836 | 0.86 | MAP4K1 (0.63) | MAP4K1ALKMET | |
| Phosphine SCHEMBL24870174 | 0.86 | MAP4K1 (0.64) | MAP4K1ALKMET | |
| Phosphine SCHEMBL25950804 | 0.85 | MAP4K1 (0.61) | MAP4K1ALK | |
| Phosphine SCHEMBL25950677 | 0.85 | MAP4K1 (0.63) | MAP4K1ALKMET | |
| Phosphine SCHEMBL25950782 | 0.84 | ALK (0.62) | MAP4K1ALKMET | |
| Phosphine SCHEMBL25950858 | 0.83 | MAP4K1 (0.60) | MAP4K1ALKMET | |
| Phosphine SCHEMBL25950342 | 0.82 | ALK (0.61) | MAP4K1ALK | |
| Phosphine SCHEMBL25950732 | 0.82 | ALK (0.66) | MAP4K1ALKMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023281417-A1 | PYRIMIDINE COMPOUNDS FOR USE AS MAP4K1 INHIBITORS | GLENMARK SPECIALTY S.A. (CH) | 2023-01-12 | — | — | WO | disclosed |