Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14687597 | 0.90 | MAOB (0.43) | MAOBMAOAGPR119ALDH1A1RAB9A | |
| SCHEMBL220638 | 0.88 | MAOB (0.46) | MAOBMAOAGPR119ALDH1A1CHRM2 | |
| SCHEMBL220637 | 0.88 | MAOB (0.46) | MAOBMAOAGPR119ALDH1A1CHRM2 | |
| SCHEMBL15304583 | 0.86 | SLC6A2 (0.48) | MAOBMAOAGPR119ALDH1A1CHRM2 | |
| SCHEMBL741083 | 0.86 | SLC6A2 (0.48) | MAOBMAOAGPR119ALDH1A1CHRM2 | |
| SCHEMBL741084 | 0.86 | SLC6A2 (0.48) | MAOBMAOAGPR119ALDH1A1CHRM2 | |
| SCHEMBL1091835 | 0.85 | MAOB (0.44) | MAOBMAOAGPR119CHRM2CHRM1 | |
| SCHEMBL3183936 | 0.85 | MAOB (0.44) | MAOBMAOAGPR119ALDH1A1RAB9A | |
| SCHEMBL1091288 | 0.85 | MAOB (0.44) | MAOBMAOAGPR119ALDH1A1RAB9A | |
| SCHEMBL1091768 | 0.85 | MAOB (0.44) | MAOBMAOAGPR119CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012000881-A1 | CHROMEN-2-ONE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2012-01-05 | — | — | WO | disclosed |