SCHEMBL2487257

SCHEMBL2487257

O=C(Nc1cncc(-c2cccc(Cl)c2)n1)c1ccc(Oc2cc3c(cc2Cl)CCCO3)cc1

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 14/20 0.51
GRM5 P41594 3/20 0.41
BRAF P15056 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2492752 0.92 PTGDR2 (0.56) PTGDR2
SCHEMBL2490747 0.91 PTGDR2 (0.61) PTGDR2GRM5
SCHEMBL2492508 0.88 PTGDR2 (0.48) PTGDR2GRM5
SCHEMBL2489767 0.86 PTGDR2 (0.44) PTGDR2GRM5
SCHEMBL2486854 0.86 PTGDR2 (0.49) PTGDR2GRM5
SCHEMBL2489639 0.85 PTGDR2 (0.45) PTGDR2
SCHEMBL2489612 0.85 PTGDR2 (0.48) PTGDR2GRM5
SCHEMBL2489821 0.85 PTGDR2 (0.69) PTGDR2GRM5
SCHEMBL2492708 0.83 PTGDR2 (0.45) PTGDR2GRM5
SCHEMBL2130251 0.83 PTGDR2 (0.75) PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2379535-A1 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES Array Biopharma Inc. (US) 2011-10-26 EP disclosed