Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 2/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12327206 | 0.77 | TTR (0.42) | TTRENPP2LPLLIPG | |
| SCHEMBL27004923 | 0.75 | IDH2 (0.31) | — | |
| SCHEMBL24874053 | 0.71 | HIF1A (0.37) | TTRHIF1A | |
| SCHEMBL21872491 | 0.70 | IL1B (0.34) | — | |
| SCHEMBL21936271 | 0.68 | — | — | |
| SCHEMBL12327211 | 0.67 | TTR (0.38) | TTRENPP2LPLLIPG | |
| SCHEMBL13334093 | 0.64 | TTR (0.46) | TTRENPP2 | |
| SCHEMBL27005957 | 0.63 | FFAR1 (0.40) | HIF1ALPLLIPG | |
| SCHEMBL24873778 | 0.63 | — | — | |
| SCHEMBL19936608 | 0.62 | CYP3A4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280283-A1 | COMPOUND USED AS SHP2 INHIBITOR AND USE THEREOF | 浙江同源康医药股份有限公司 | 2023-01-12 | — | — | WO | disclosed |