Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24876676 | 0.76 | LMNA (0.38) | LMNAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL24876675 | 0.76 | LMNA (0.38) | LMNAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL24876007 | 0.74 | LMNA (0.80) | LMNAPKMTHRBMAPTMEN1 | |
| SCHEMBL24876203 | 0.72 | GRIN2D (0.39) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL24876267 | 0.69 | KDM4E (0.37) | LMNAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL24876254 | 0.69 | PDE3B (0.46) | PKMGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL24876758 | 0.67 | LMNA (0.52) | LMNAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL24876374 | 0.67 | LMNA (0.62) | LMNAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL24875986 | 0.66 | GRIN2D (0.61) | LMNAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5769722 | 0.64 | GRIN2D (1.00) | LMNAGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |