Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | IDH1 | O75874 | 2/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31236109 | 1.00 | FFAR4 (0.51) | FFAR4ATMIDH1KIF11MAPT | |
| SCHEMBL30210923 | 0.87 | FFAR4 (0.47) | FFAR4ATMIDH1KIF11MAPT | |
| SCHEMBL24876322 | 0.81 | MAPT (0.49) | ATMIDH1KIF11MAPTSMN1; SMN2 | |
| SCHEMBL31236141 | 0.81 | FFAR4 (0.64) | FFAR4ATMIDH1KIF11MAPT | |
| SCHEMBL24876157 | 0.81 | FFAR4 (0.64) | FFAR4ATMIDH1KIF11MAPT | |
| SCHEMBL30210899 | 0.79 | ATM (0.42) | FFAR4ATMIDH1KIF11MAPT | |
| SCHEMBL24876035 | 0.78 | FFAR4 (0.51) | FFAR4ATMIDH1KIF11MAPT | |
| SCHEMBL30210908 | 0.78 | FFAR4 (0.51) | FFAR4ATMIDH1KIF11MAPT | |
| SCHEMBL24876248 | 0.74 | DHODH (0.39) | FFAR4MAPTKCNH2 | |
| SCHEMBL23415910 | 0.72 | IDH1 (0.51) | FFAR4ATMIDH1KIF11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |