Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 12/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.34 |
| ▸ | AADAC | P22760 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24876167 | 0.79 | FFAR4 (0.47) | EPHX2FFAR4MAPTKDM4EKCNH2 | |
| SCHEMBL24876247 | 0.74 | FFAR4 (0.51) | FFAR4MAPTKCNH2 | |
| SCHEMBL31236109 | 0.74 | FFAR4 (0.51) | FFAR4MAPTKCNH2 | |
| SCHEMBL21617078 | 0.70 | GPR3 (0.40) | FFAR4SCN5ASCN9A | |
| SCHEMBL24876191 | 0.67 | MAPT (0.45) | EPHX2FFAR4MAPTFAAHTDP1 | |
| SCHEMBL10957619 | 0.66 | EPHX2 (0.45) | DHODHEPHX2MAPTKDM4ETDP1 | |
| SCHEMBL24876210 | 0.66 | FFAR4 (0.45) | EPHX2FFAR4MAPTTDP1L3MBTL1 | |
| SCHEMBL30210923 | 0.66 | FFAR4 (0.47) | FFAR4MAPTKCNH2 | |
| SCHEMBL20526515 | 0.65 | HRH4 (0.43) | EPHX2EPHX1FFAR4SCN5ASCN9A | |
| SCHEMBL4564168 | 0.63 | L3MBTL1 (0.47) | DHODHEPHX2EPHX1MAPTFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |